产品货号：
Z18747
中文名称：
IA-1/INSM1抗体
英文名称：
Anti-IA-1/INSM1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IA-1/INSM1 Antibody |
| 指标别名 | IA1;IA-1;IA1;Insulinoma-associated protein 1;Zinc finger protein IA-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | INSM1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | IA-1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1.The immunogen is located within amino acids 90 - 140 of IA-1. |
| 计算分子量 | 53kDa |
| 成分 | IA-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | IA-1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | IA-1,also known as INSM1,is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library,is expressed in the developing nervous system.Specifically,IA-1 is expressed as early as E9.5 in mice in the fore-,mid- and hindbrain,spinal cord,retina,and olfactory bulb.It is thought that IA-1 functions as a transcriptional repressor,and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation.IA-1 is also expressed in multiple tumors,including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas,indicating that IA-1 may be an important target in cancer therapy. |
| Uniprot ID | Q01101 |
| 基因名全称 | Insulinoma-associated 1 |
| 蛋白名全称 | Insulinoma-associated 1 |
| 推荐稀释比 | IA-1 antibody can be used for detection of IA-1 by Western blot at 1μg/mL.Antibody validated:Western Blot in rat samples.All other applications and species not yet tested. |
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